Lentztrehalose A [1609356-99-1]

TargetMol Chemicals

Lentztrehalose A [1609356-99-1]

999

Research Use Only

Lentztrehalose A

C17H32O13

444.43

Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase-an enzyme involved in trehalose metabolism-more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.

3 years

O([C@H]1O[C@H](CO)[C@@H](OC[C@@H](C(C)(C)O)O)[C@H](O)[C@H]1O)[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O

-20°C

12352200