Lenumlostat (hydrochloride)

MedChem Express

Lenumlostat (hydrochloride) [2098884-53-6]

10

2098884-53-6

Research Use Only

C18H18ClF4N3O3

435.80

PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 ( LOXL2 ) inhibitor, with IC 50 s of 0.71 and 1.17 microM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 ( IC 50 s, 0.10, 0.12, and 0.16 microM, respectively). PAT-1251 Hydrochloride is used in the research of fibrotic diseases.

O=C(C1=CC=CC(OC2=NC(C(F)(F)F)=CC(CN)=C2)=C1)N3C[C@@H](F)[C@H](O)C3.Cl

12352200