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Leoidin [105350-54-7]

HY-N8497
MedChem Express
CAS Number105350-54-7
Product group Chemicals
Molecular Weight413.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leoidin [105350-54-7]
  • Delivery Days Customer
    5
  • CAS Number
    105350-54-7
  • Category Supplier
    CHEMICAL,general_chemicals_reagents
  • Certification
    Research Use Only
  • Molecular Formula
    C18H14Cl2O7
  • Molecular Weight
    413.21
  • Scientific Description
    Leoidin is an OATP1B1 and OATP1B3 inhibitor with Ki values of 0.08 and 1.84 microM, respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC50= 42 microM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides[1][2].
  • SMILES
    O=C(C1=C(O)C(C)=C(C(OC2=C(Cl)C(O)=C(Cl)C(C)=C23)=C1C)OC3=O)OC
  • UNSPSC
    12352005