Leptomycin B
HY-16909
Overview
- SupplierMedChem Express
- Product NameLeptomycin B [87081-35-4]
- Delivery Days Customer10
- CAS Number87081-35-4
- CertificationResearch Use Only
- Estimated Purity99.94
- Molecular FormulaC33H48O6
- Molecular Weight540.73
- Scientific DescriptionLeptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1].
- SMILESO=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O
- Storage Instruction-20°C
- UNSPSC12352200