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Lestaurtinib [111358-88-4]

Lestaurtinib [111358-88-4]

T15738
TargetMol Chemicals
CAS Number111358-88-4
Product group Chemicals
Estimated Purity99.17%
Molecular Weight439.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Lestaurtinib [111358-88-4]
  • Delivery Days Customer
    16
  • CAS Number
    111358-88-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.17%
  • Molecular Formula
    C26H21N3O4
  • Molecular Weight
    439.46
  • Scientific Description
    Lestaurtinib (CEP 701) is an orally available and selective inhibitor of FMS-like tyrosine kinase-3 (FLT3, IC50: 0.9 nM), which inhibits FLT3 autophosphorylation in vitro.Lestaurtinib promotes the expression of c-MYC, inhibits the phosphorylation of RPTKs, and has high affinity for TrkA and JAK2. Lestaurtinib promotes c-MYC expression, inhibits phosphorylation of RPTKs, has a high affinity for TrkA and JAK2, induces apoptosis and cell growth arrest, and can be used to study leukemia.
  • SMILES
    C[C@]12N3C=4C=5N(C=6C(C5C7=C(C4C=8C3=CC=CC8)CNC7=O)=CC=CC6)[C@](O1)(C[C@@]2(CO)O)[H]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200