Bio-Connect

Leteprinim [138117-50-7]

HY-120251
MedChem Express
CAS Number138117-50-7
Product group Chemicals
Molecular Weight327.29
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leteprinim [138117-50-7]
  • Delivery Days Customer
    5
  • CAS Number
    138117-50-7
  • Certification
    Research Use Only
  • Molecular Formula
    C15H13N5O4
  • Molecular Weight
    327.29
  • Scientific Description
    Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species[1][2][3][4].
  • SMILES
    O=C(O)C1=CC=C(NC(CCN2C=NC3=C2NC=NC3=O)=O)C=C1
  • UNSPSC
    12352200