Leu-AMS [288591-93-5]

TargetMol Chemicals

Leu-AMS [288591-93-5]

72

288591-93-5

Chemical

Research Use Only

Leu-AMS

C16H25N7O7S

459.48

Leu-AMS, a leucine analogue and potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, exhibits cytotoxic effects in both cancer and normal cells and hampers bacterial growth. It specifically inhibits LRSs catalytic activity without impacting the leucine-induced activation of mTORC1.

3 years

CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

-20°C

12352200