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Leu-AMS

HY-108900
MedChem Express
CAS Number288591-93-5
Product group Chemicals
Estimated Purity98.08
Molecular Weight459.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leu-AMS [288591-93-5]
  • Delivery Days Customer
    10
  • CAS Number
    288591-93-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.08
  • Molecular Formula
    C16H25N7O7S
  • Molecular Weight
    459.48
  • Scientific Description
    Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase ( LRS ) with an IC 50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria [1] .
  • SMILES
    O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CC(C)C)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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