Leu-AMS
HY-108900
Overview
- SupplierMedChem Express
- Product NameLeu-AMS [288591-93-5]
- Delivery Days Customer10
- CAS Number288591-93-5
- CertificationResearch Use Only
- Estimated Purity98.08
- Molecular FormulaC16H25N7O7S
- Molecular Weight459.48
- Scientific DescriptionLeu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase ( LRS ) with an IC 50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria [1] .
- SMILESO[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CC(C)C)=O)=O
- Storage Instruction-20°C
- UNSPSC12352200