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Leukadherin-1

HY-15701
MedChem Express
CAS Number344897-95-6
Product group Chemicals
Estimated Purity98.0
Molecular Weight421.49
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leukadherin-1 [344897-95-6]
  • Delivery Days Customer
    10
  • CAS Number
    344897-95-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C22H15NO4S2
  • Molecular Weight
    421.49
  • Scientific Description
    Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18 , increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC 50 of 4 microM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling [1] [2] [3] .
  • SMILES
    O=C(O)C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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