Levacetylleucine [1188-21-2]

MedChem Express

Levacetylleucine [1188-21-2]

10

1188-21-2

Research Use Only

98.0

C8H15NO3

173.21

Levacetylleucine (N-acetyl-L-leucine), an orally bioavailable and brain-penetrant compound, is an acetylated derivative of amino acid Leucine. Levacetylleucine is the active form of N-acetyl-leucine (NAL). Levacetylleucine attenuates neuronal death and neuroinflammation in the cortical tissue of mice. Levacetylleucine also potentially improves ameliorates lysosomal and metabolic dysfunction. Levacetylleucine improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats. Levacetylleucine is promising for research of neurological manifestations of Niemann-Pick disease type C, traumatic brain injury and neurodegeneration prevention[1][2][3][4].

CC(C)C[C@H](NC(C)=O)C(O)=O

-20°C,2°C to 8°C

12352200