Levistolide A

MedChem Express

Levistolide A [88182-33-6]

9

88182-33-6

Research Use Only

99.26

C24H28O4

380.48

Levistolide A is an apoptosis inducer and a PEDV virus inhibitor. Levistolide A can induce apoptosis in colon cancer cells and suppress the replication of porcine epidemic diarrhea virus ( PEDV ) by promoting ROS generation. Levistolide A activates peroxisome proliferator-activated receptor gamma ( PPARgamma ) in N2a/APP695swe cells and reduces excessive phosphorylation of tau through the GSK3alpha/beta pathway, improving symptoms in Alzheimers mice. Levistolide A improves kidney damage in 5/6 nephrectomy (Nx) mice by inhibiting the RAS , TGF-beta1/Smad , and MAPK pathways [1] [2] [3] [4] .

O=C(O/C([C@@]1(CC2)[C@]34[H])=C\CCC)C1=C[C@]2([H])[C@]3([H])CCC5=C4C(O/C5=C\CCC)=O

-20°C,2°C to 8°C

12352200