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Levomilnacipran-d10 (hydrochloride)

HY-14794AS
MedChem Express
Molecular Weight292.87
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Levomilnacipran-d10 (hydrochloride) [2747914-23-2]
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C15H13D10ClN2O
  • Molecular Weight
    292.87
  • Scientific Description
    Levomilnacipran-d10 ((1S,2R)-Milnacipran-d10) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression[1][2].
  • SMILES
    O=C([C@]1(C2=CC=CC=C2)[C@H](CN)C1)N(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H].Cl
  • UNSPSC
    12131703