Levomilnacipran-d10 (hydrochloride)
HY-14794AS
Overview
- SupplierMedChem Express
- Product NameLevomilnacipran-d10 (hydrochloride) [2747914-23-2]
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC15H13D10ClN2O
- Molecular Weight292.87
- Scientific DescriptionLevomilnacipran-d10 ((1S,2R)-Milnacipran-d10) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression[1][2].
- SMILESO=C([C@]1(C2=CC=CC=C2)[C@H](CN)C1)N(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H].Cl
- UNSPSC12131703