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Lexibulin

HY-10498
MedChem Express
CAS Number917111-44-5
Product group Chemicals
Estimated Purity99.50
Molecular Weight434.53
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lexibulin [917111-44-5]
  • Delivery Days Customer
    10
  • CAS Number
    917111-44-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.50
  • Molecular Formula
    C24H30N6O2
  • Molecular Weight
    434.53
  • Scientific Description
    Lexibulin (CYT-997) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo [1] [2] . Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells [3] .
  • SMILES
    CCC[C@H](NC1=C(C)C=NC(C2=CC=C(NC(NCC)=O)C(OC)=C2)=N1)C3=CN=CC=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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