Lexibulin (dihydrochloride)
HY-10498A
CAS Number917111-49-0
Product group Chemicals
Molecular Weight507.46
Overview
- SupplierMedChem Express
- Product NameLexibulin (dihydrochloride) [917111-49-0]
- Delivery Days Customer10
- CAS Number917111-49-0
- CertificationResearch Use Only
- Molecular FormulaC24H32Cl2N6O2
- Molecular Weight507.46
- Scientific DescriptionLexibulin dihydrochloride (CYT-997 dihydrochloride) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo [1] [2] . Lexibulin dihydrochloride induces cell apoptosis and induces mitochondrial ROS generation in GC cells [3] .
- SMILESCCC[C@H](NC1=C(C)C=NC(C2=CC=C(NC(NCC)=O)C(OC)=C2)=N1)C3=CN=CC=C3.[H]Cl.[H]Cl
- UNSPSC12352200