Bio-Connect

LF / LTF / Lactoferrin Protein (Native) (Full Length)

Research Use Only
LS-G132072
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    LF / LTF / Lactoferrin Protein (Native) (Full Length)
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Concentration
    10.9 mg/ml
  • Estimated Purity
    >95%
  • Scientific Description
    Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352202