LG190178 [233268-81-0]
HY-117182
CAS Number233268-81-0
Product group Chemicals
Molecular Weight458.63
Overview
- SupplierMedChem Express
- Product NameLG190178 [233268-81-0]
- Delivery Days Customer5
- CAS Number233268-81-0
- CertificationResearch Use Only
- Molecular FormulaC28H42O5
- Molecular Weight458.63
- Scientific DescriptionLG190178 is a non-steroidal vitamin D receptor (VDR) ligand that can induce the formation of heterodimer complexes between VDR and retinoid X receptor (RXR), stabilizing the agonistic conformation of the VDR ligand-binding domain and promoting its interaction with co-activators. LG190178 has functions in regulating calcium homeostasis, bone mineralization, as well as cell proliferation, differentiation, and apoptosis, making it useful for research in psoriasis, osteoporosis, and cancer[1].
- SMILESOCC(O)COC1=CC=C(C(C2=CC=C(OCC(O)C(C)(C)C)C(C)=C2)(CC)CC)C=C1C
- UNSPSC12352200