LGK974 [1243244-14-5]

TargetMol Chemicals

LGK974 [1243244-14-5]

4

1243244-14-5

Chemical

Research Use Only

LGK974

99.80%

C23H20N6O

396.44

LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.

3 years

Cc1cc(ccn1)-c1ncc(CC(=O)Nc2ccc(cn2)-c2cnccn2)cc1C

-20°C

12352200