LGP2, Human (HEK293, FLAG)

MedChem Express

LGP2, Human (HEK293, FLAG)

14

Research Use Only

98.0

DHX58

DExH-box helicase 58

D11LGP2, D11lgp2e, LGP2, RLR-3, ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, DEXH (Asp-Glu-X-His) box polypeptide 58, RIG-I-like receptor 3, RIG-I-like receptor LGP2, RLR, RNA helicase LGP2, ortholog of mouse D11lgp2, probable ATP-dependent RNA helicase DHX58, probable ATP-dependent helicase LGP2, protein D11Lgp2 homolog

ATP-dependent RNA helicase DHX58

LGP2 protein is a key regulator of RIGI- and IFIH1/MDA5-mediated antiviral signaling and has dual negative and positive functions affected by factors such as infected viruses and target cells. LGP2 lacks a CARD domain for independent initiation of antiviral signaling and therefore inhibits RIG-I through multiple mechanisms, including competition for RNA binding and obstruction of interaction with MAVS/IPS1. LGP2 Protein, Human (HEK293, FLAG) is the recombinant human-derived LGP2 protein, expressed by HEK293 , with C-Flag labeled tag.

-80°C

41116100

Human