Lgr5/GPR49, Human (CHO, hFc)
HY-P79308
Protein IDO75473
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameLgr5/GPR49, Human (CHO, hFc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity93.67
- Protein IDO75473
- Protein NameLeucine-rich repeat-containing G-protein coupled receptor 5
- Scientific DescriptionThe Lgr5/GPR49 protein is a receptor for R-spondins that enhances the canonical Wnt signaling pathway and marks stem cells in the intestinal epithelium and hair follicles. Lgr5/GPR49 binds R-spondins (RSPO1-4), binds to phosphorylated LRP6 and Frizzled receptors, initiates Wnt signaling and amplifies target gene expression. Lgr5/GPR49 Protein, Human (CHO, hFc) is the recombinant human-derived Lgr5/GPR49 protein, expressed by CHO , with C-hFc labeled tag. The total length of Lgr5/GPR49 Protein, Human (CHO, hFc) is 539 a.a., with molecular weight of 88-110 kDa.
- Storage Instruction-20°C
- UNSPSC12352202