Lgr5/GPR49, Human (CHO, hFc)
HY-P79308
Protein IDO75473
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameLgr5/GPR49, Human (CHO, hFc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity93.67
- Gene ID8549
- Target nameLGR5
- Target descriptionleucine rich repeat containing G protein-coupled receptor 5
- Target synonymsFEX; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine-rich repeat-containing G-protein coupled receptor 5; orphan G protein-coupled receptor HG38
- Protein IDO75473
- Protein NameLeucine-rich repeat-containing G-protein coupled receptor 5
- Scientific DescriptionThe Lgr5/GPR49 protein is a receptor for R-spondins that enhances the canonical Wnt signaling pathway and marks stem cells in the intestinal epithelium and hair follicles. Lgr5/GPR49 binds R-spondins (RSPO1-4), binds to phosphorylated LRP6 and Frizzled receptors, initiates Wnt signaling and amplifies target gene expression. Lgr5/GPR49 Protein, Human (CHO, hFc) is the recombinant human-derived Lgr5/GPR49 protein, expressed by CHO , with C-hFc labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100
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