Liarozole (dihydrochloride)

MedChem Express

Liarozole (dihydrochloride) [1883548-96-6]

10

1883548-96-6

Research Use Only

99.0

C17H15Cl3N4

381.69

Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA) . Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA ( IC 50 =7 microM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties [1] [2] [3] .

ClC1=CC(C(C2=CC=C3N=CNC3=C2)N4C=CN=C4)=CC=C1.[H]Cl.[H]Cl

2°C to 8°C

12352200