Liarozole HCl [145858-50-0]

TargetMol Chemicals

Liarozole HCl [145858-50-0]

72

145858-50-0

Research Use Only

Liarozole HCl

C17H14Cl2N4

345.23

Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. It also inhibits aromatase.

3 years

Cl.ClC1=CC=CC(=C1)C(C=2C=CC=3N=CNC3C2)N4C=NC=C4

-20°C

12352200