LIN28 inhibitor LI71

MedChem Express

LIN28 inhibitor LI71 [1357248-83-9]

9

1357248-83-9

Research Use Only

98.20

C21H21NO3

335.40

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC 50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28s activity against let-7 in leukemia cells and embryonic stem cells [1] .

O=C(O)C1=CC=C([C@@H]2NC3=C(C=CC=C3OCC)[C@@]4([H])[C@]2([H])CC=C4)C=C1

-20°C,2°C to 8°C

12352200