LIN28 inhibitor LI71 enantiomer

MedChem Express

LIN28 inhibitor LI71 enantiomer [956189-58-5]

10

956189-58-5

Research Use Only

99.68

C21H21NO3

335.40

LIN28 inhibitor LI71 enantiomer is the less active enantiomer of LIN28 inhibitor LI71 (HY-123905). LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 microM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 microM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and alpha/beta tubulin and has an inhibitory effect on Plasmodium falciparum[1][2].

O=C(O)C1=CC=C([C@H]2NC3=C(C=CC=C3OCC)[C@]4([H])[C@@]2([H])CC=C4)C=C1

-20°C,2°C to 8°C

12352200