Lin28-let-7 antagonist 1 [108825-65-6]

MedChem Express

Lin28-let-7 antagonist 1 [108825-65-6]

10

108825-65-6

Research Use Only

99.68

C15H15N5O

281.32

Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 microM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells[1].

CN(C(C)=O)C1=CC=CC(C2=NN3C(C)=NN=C3C=C2)=C1

-20°C,2°C to 8°C

12352200