
WB analysis of extracts from HeLa and 293 cells using GTX50820 LIN28B antibody.
LIN28B antibody
GTX50820
Overview
- SupplierGeneTex
- Product NameLIN28B antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID389421
- Target nameLIN28B
- Target descriptionlin-28 homolog B
- Target synonymsCSDD2; Lin-28.2; lin-28B; protein lin-28 homolog B
- HostRabbit
- IsotypeIgG
- Protein IDQ6ZN17
- Protein NameProtein lin-28 homolog B
- Scientific DescriptionThe protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3 UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203