LIN7C Polyclonal Antibody

Reddot Biotech

LIN7C Polyclonal Antibody

5

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LIN7C

lin-7 cell polarity scaffold C

LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3, protein lin-7 homolog C, LIN-7 protein 3, lin-7 homolog C, crumbs cell polarity complex component, mammalian LIN-7 3, mammalian lin-seven protein 3, veli-3, vertebrate LIN7 homolog 3, vertebrate lin-7 homolog 3

Rabbit

IgG

Protein lin-7 homolog C

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C, CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA receptor subunit NR2B along microtubules (By similarity. This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12 and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. - This is a LIN7C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

-20°C

41116161