Linarin [480-36-4]

TargetMol Chemicals

Linarin [480-36-4]

9

480-36-4

Chemical

Research Use Only

Linarin

98.99%

C28H32O14

592.55

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-beta-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-alpha-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

3 years

COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC3OC(COC4OC(C)C(O)C(O)C4O)C(O)C(O)C3O)cc2o1

-20°C

12352200