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Lipoxin A4

HY-113509
MedChem Express
CAS Number89663-86-5
Product group Chemicals
Estimated Purity98.00
Molecular Weight352.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lipoxin A4 [89663-86-5]
  • Delivery Days Customer
    10
  • CAS Number
    89663-86-5
  • Certification
    Research Use Only
  • Concentration
    283.71 uM
  • Estimated Purity
    98.00
  • Molecular Formula
    C20H32O5
  • Molecular Weight
    352.47
  • Scientific Description
    Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM[3].
  • SMILES
    CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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