Lipoxin A4

MedChem Express

Lipoxin A4 [89663-86-5]

10

89663-86-5

Research Use Only

283.71 uM

99.19

C20H32O5

352.47

Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties [1] . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways [2] . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM [3] .

CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O

-20°C

12352200