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Liprin alpha 1 antibody [N1N2], N-term

Research Use Only
GTX115098
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPFIA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Liprin alpha 1 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.98 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID8500
  • Target name
    PPFIA1
  • Target description
    PTPRF interacting protein alpha 1
  • Target synonyms
    LAR-interacting protein 1; LIP.1; LIP1; LIP-1; LIPRIN; Liprin-alpha1; liprin-alpha-1; protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13136
  • Protein Name
    Liprin-alpha-1
  • Scientific Description
    The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Liprin-alpha-1 is a novel component of the murine neuromuscular junction and is involved in the organization of the postsynaptic machinery. Bernadzki KM et al., 2017 Aug 22, Sci Rep
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  • alpha-Dystrobrevin-1 recruits Grb2 and alpha-catulin to organize neurotransmitter receptors at the neuromuscular junction. Gingras J et al., 2016 Mar 1, J Cell Sci
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