LKY-047 [1954681-29-8]

MedChem Express

LKY-047 [1954681-29-8]

5

1954681-29-8

Research Use Only

99.94

C23H19NO7

421.40

LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 microM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A[1].

O=C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)/C=C/C4=CC=C([N+]([O-])=O)C=C4

-20°C,2°C to 8°C

12352200