LLK203

MedChem Express

LLK203

14

Research Use Only

98.58

C28H23N3O4S3

561.69

LLK203 is a potent USP2/USP8 dual-target inhibitor with IC50s of 0.89 microM and 0.52 microM, respectively. LLK203 leads a degradation of ERalpha and induces apoptosis of breast cancer MCF-7 cells. LLK203 demonstrates antitumor activities against the 4T1 tumor mice model[1].

O=C(C1=CC=C(OC)C=C1NS(=O)(C2=CC=C(C3=CC=C(C)S3)C=C2)=O)NC4=NC(C5=CC=CC=C5)=CS4

-20°C,2°C to 8°C

12352200