LM11A-31

MedChem Express

LM11A-31 [102562-74-3]

9

102562-74-3

Research Use Only

95.0

C12H25N3O2

243.35

LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimers disease mouse models with mid- to late-stage disease progression [1] [2] .

CC[C@H](C)[C@H](N)C(NCCN1CCOCC1)=O

-20°C

12352200