Lobeglitazone [607723-33-1]

MedChem Express

Lobeglitazone [607723-33-1]

14

607723-33-1

Research Use Only

95.83

C24H24N4O5S

480.54

Lobeglitazone is a new type of thiazolidinedione. Lobeglitazone is the orally active agonist for PPAR with EC50 of 137.4 nM and 546.3 nM for PPARgamma and PPARalpha. Lobeglitazone is the inhibitor for ERK/JNK/Smad/NF-kappaB signaling pathway. Lobeglitazone exhibits anti-inflammatory, anti-diabetic, anti-fibrotic and anti-atherosclerotic properties[1][2][3][4][5][6].

O=C(SC1CC2=CC=C(C=C2)OCCN(C)C3=NC=NC(OC4=CC=C(C=C4)OC)=C3)NC1=O

-20°C,2°C to 8°C

12131703