Lobeline [90-69-7]

MedChem Express

Lobeline [90-69-7]

10

90-69-7

Research Use Only

C22H27NO2

337.46

Lobeline (alpha-Lobeline) is a brain-penetrant nicotinic receptor agonist. Lobeline increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage. Lobeline is effective in smoking cessation[1][2].

CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3

12352200