Lomibuvir [1026785-55-6]

TargetMol Chemicals

Lomibuvir [1026785-55-6]

9

1026785-55-6

Chemical

Research Use Only

Lomibuvir

C25H35NO4S

445.61

Lomibuvir (VCH-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis [1].

3 years

CC1CCC(CC1)C(=O)N(C1CCC(O)CC1)c1cc(sc1C(O)=O)C#CC(C)(C)C

-20°C

12352200