Lorlatinib (Standard)

MedChem Express

Lorlatinib (Standard) [1454846-35-5]

5

Research Use Only

99.92

Lorlatinib (Standard) is the analytical standard of Lorlatinib. This product is intended for research and analytical applications. Lorlatinib (PF-06463922) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib has K i s of L1196M , respectively. Lorlatinib targets to EML4-ALK, and inhibits ALK phosphorylation with IC 50 s of 15-43 nM (ALK L1196 ), 14-80 nM (ALK G1269A ), 38-50 nM (ALK 1151Tins ), 77-113 nM (ALK G1202R ), respectively [1] [2] [3] .

2°C to 8°C

41116135