Lornoxicam [70374-39-9]

MedChem Express

Lornoxicam [70374-39-9]

10

70374-39-9

Research Use Only

99.36

C13H10ClN3O4S2

371.82

Lornoxicam (Chlortenoxicam) is an orally active oxycontin nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, antipyretic and anticancer activities. Lornoxicam exhibits good inhibitory effects on both COX-1 and COX-2 (COX-1: IC50=0.005 microM; COX-2:IC50=0.008 microM) and inhibits the production of NO by iNOS (IC50=65 microM) and the proinflammatory cytokine IL-6 (IC50=54 microM). Lornoxicam also inhibits tumor cell proliferation and migration and induces tumor cell apoptosis. Lornoxicam can be used in the study of inflammatory pain, colorectal cancer and breast cancer[1][2][3][4][5][6][7].

O=C(C1=C(O)C2=C(C=C(Cl)S2)S(N1C)(=O)=O)NC3=NC=CC=C3

-20°C,2°C to 8°C

12352200