Losartan Carboxylic Acid [124750-92-1]
HY-12765
CAS Number124750-92-1
Product group Chemicals
Estimated Purity99.26
Molecular Weight436.89
Overview
- SupplierMedChem Express
- Product NameLosartan Carboxylic Acid [124750-92-1]
- Delivery Days Customer10
- CAS Number124750-92-1
- CertificationResearch Use Only
- Estimated Purity99.26
- Molecular FormulaC22H21ClN6O2
- Molecular Weight436.89
- Scientific DescriptionLosartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].
- SMILESO=C(C1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
Related products
Product group Chemicals
CAS Number124750-92-1
Molecular Weight436.89 g/mol
- SizePrice
![Losartan Carboxylic Acid [124750-92-1]](https://www.targetmol.com/group3/M00/02/87/CgoaEGY7NiGEQNXJAAAAANOHoOI851.png)
Product group Chemicals
CAS Number124750-92-1
Estimated Purity99.28%
Molecular Weight436.89
- SizePrice
