Loureirin B
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S3242
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameLoureirin B
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionLoureirin B (LB, LrB), a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of PAI-1 with IC50 of 26.10 muM. Loureirin B downregulates p-ERK and p-JNK in TGF-bèta1-stimulated fibroblasts. Loureirin B promotes insulin secretion mainly through increasing Pdx-1, MafA, intracellular ATP level, inhibiting the KATP current, influx of Ca2+ to the intracellular.
- UNSPSC12352200