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ProductsBack/LOX antibody [6B11]
IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.

LOX antibody [6B11]

GTX84182
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetLOX
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Overview

  • Supplier
    GeneTex
  • Product Name
    LOX antibody [6B11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    6B11
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4015
  • Target name
    LOX
  • Target description
    lysyl oxidase
  • Target synonyms
    AAT10; protein-lysine 6-oxidase
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP28300
  • Protein Name
    Protein-lysine 6-oxidase
  • Scientific Description
    Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol Lett
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  • Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts. Goggins E et al., 2018 Feb, Neoplasia
    Read more