IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
LOX antibody [6B11]
GTX84182
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLOX
Overview
- SupplierGeneTex
- Product NameLOX antibody [6B11]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6B11
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4015
- Target nameLOX
- Target descriptionlysyl oxidase
- Target synonymsAAT10; protein-lysine 6-oxidase
- HostMouse
- IsotypeIgG1
- Protein IDP28300
- Protein NameProtein-lysine 6-oxidase
- Scientific DescriptionResponsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol LettRead more
- Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts. Goggins E et al., 2018 Feb, NeoplasiaRead more