LP-130 [153314-49-9]

MedChem Express

LP-130 [153314-49-9]

9

153314-49-9

Research Use Only

C45H58N6O7

794.98

LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition.

NC([C@H](CC1=CC=CC2=C1C=CC=C2)NC([C@H](CC)NC(C[C@H](O)[C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC3=CC=CC4=C3C=CC=C4)=O)=O)=O)=O)=O

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