LP-403812 [1142050-84-7]

MedChem Express

LP-403812 [1142050-84-7]

5

1142050-84-7

Research Use Only

C26H34N6O2S

494.65

LP-403812 is a high affinity proline transporter (PROT) inhibitor that produces dose-dependent inhibition of hPROT (IC50=0.11 microM; Ki=0.12 microM) and also inhibits the activity of mouse brain synaptosomal mPROT with the same potency (IC50=0.23 microM). LP-403812 can be used to study the function of PROT in the brain[1].

O=C(NC1=NC(N(C(C)(C)C)N=C2C(N3[C@H](CN4CCCC4)CCC3)=O)=C2S1)C5=CC=C(C)C=C5

12352200