
Western blot analysis of extracts from COLO205 cells, using LRAT antibody.
LRAT Antibody
CSB-PA295134
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLRAT
Overview
- SupplierCusabio
- Product NameLRAT Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9227
- Target nameLRAT
- Target descriptionlecithin retinol acyltransferase
- Target synonymsLCA14; lecithin retinol acyltransferase; lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
- HostRabbit
- IsotypeIgG
- Protein IDO95237
- Protein NameLecithin retinol acyltransferase
- Scientific DescriptionTransfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Ruiz A., J. Biol. Chem. 274:3834-3841(1999). Mondal M.S., Biochemistry 39:5215-5220(2000). Thompson D.A., Nat. Genet. 28:123-124(2001).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203