LRP1 antibody [A2Mr alpha-2]

GeneTex

LRP1 antibody [A2Mr alpha-2]

9

This antibody detects an epitope within the LRP515 chain of LRP1 (CD91).

FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

A2Mr alpha-2

1 mg/ml

Unconjugated

LRP1

LDL receptor related protein 1

A2MR; alpha-2-macroglobulin receptor; APOER; apolipoprotein E receptor; APR; CD91; IGFBP3R; IGFBP-3R; IGFBP3R1; KPA; low density lipoprotein receptor-related protein 1; LRP; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor

Mouse

IgG1

Prolow-density lipoprotein receptor-related protein 1

This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimers disease patients. [provided by RefSeq, Oct 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203