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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013102ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013102ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013102ESR2HU at dilution of 1:100

LRP6 Antibody

CSB-PA013102ESR2HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetLRP6
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Overview

  • Supplier
    Cusabio
  • Product Name
    LRP6 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4040
  • Target name
    LRP6
  • Target description
    LDL receptor related protein 6
  • Target synonyms
    ADCAD2; low-density lipoprotein receptor-related protein 6; LRP-6; STHAG7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75581
  • Protein Name
    Low-density lipoprotein receptor-related protein 6
  • Scientific Description
    Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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