LRP6 antibody, Internal

GeneTex

LRP6 antibody, Internal

7

This antibody is expected to recognise an epitope corresponding to aa 1546-1560 of human LRP6 protein.

IHC-P: 4-6microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

LRP6

LDL receptor related protein 6

ADCAD2; low-density lipoprotein receptor-related protein 6; LRP-6; STHAG7

Goat

IgG

Low-density lipoprotein receptor-related protein 6

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203