LRPAP1 Polyclonal Antibody

Reddot Biotech

LRPAP1 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LRPAP1

LDL receptor related protein associated protein 1

39 kDa receptor-associated protein; A2MRAP; A2RAP; alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; HBP44; low density lipoprotein receptor-related protein associated protein 1; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1); MRAP; MYP23; RAP

Rabbit

IgG

Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Human, Mouse, Rat

-20°C

12352203