LRRC15 Antibody

Cusabio

LRRC15 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

LRRC15

leucine rich repeat containing 15

LIB, leucine-rich repeat-containing protein 15, hLib, leucine-rich repeat protein induced by beta amyloid, leucine-rich repeat protein induced by beta-amyloid homolog

Rabbit

IgG

Leucine-rich repeat-containing protein 15

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimers disease.

Human, Mouse, Rat

-20°C or -80°C

41116161