LSD1-IN-19

MedChem Express

LSD1-IN-19 [2983011-81-8]

10

Research Use Only

C33H42N6O2

554.73

LSD1-IN-19 (compound 29) is a potent, non-covalent and selective LSD1 inhibitor, with Ki of 0.108 microM and KD of 0.068 microM, respectively. LSD1-IN-19 shows antiproliferative activity in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with IC50 (72 h) of 0.17 and 0.40 microM, respectively[1].

COC1=CC2=C(N=C(N=C2NC3CCN(CC3)CC4=CC=CC=C4)NCCCN(C)C)C=C1OCC5=CC=CC=C5

12131703