LSD1/ER-IN-1

MedChem Express

LSD1/ER-IN-1

10

Research Use Only

C23H18FNO6S

455.46

LSD1/ER-IN-1 (compound 11g) is a potent ER and LSD1 inhibitor, with an IC50 of 1.55 microM (LSD1). LSD1/ER-IN-1 has high affinity selectivity for ERalpha protein, with alpha/beta ratio of 7.11. LSD1/ER-IN-1 shows good antiproliferative activity against MCF-7 breast cancer cells, with an IC50 of 8.79 microM[1].

O=S(C1[C@H]2C(C3=CC=C(O)C=C3)=C(C4=CC=C(O)C=C4)[C@@H](C1)O2)(OC5=NC(F)=CC=C5)=O

12131703